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Cyclerion Therapeutics Praliciguat Fails in Two Crucial Clinical Trials

Cyclerion Therapeutics (NASDAQ: CYCN), a clinical-stage Company, announced the failure of its drug candidate praliciguat in meeting the primary endpoints in two separate clinical studies, in diabetic nephropathy (DN) and heart failure with preserved ejection fraction (HFpEF). Praliciguat is a soluble guanylate cyclase (sGC) stimulator...

Aravive Reports Positive Data from Phase 1b Ovarian Cancer Trial

Aravive, Inc. (NASDAQ: ARAV), a clinical stage biotechnology Company engaged in developing therapeutics for solid tumours and hematologic malignancies, announced positive data from its ongoing Phase 1b/2 study of AVB-500, intended for treatment of Ovarian cancer patients. The results were presented at the European Society...

Will the E-Cigarette Dream Run Evaporate in Smoke?

The Food and Drug Administration of America (FDA) has initiated a criminal investigation into the supply chain of Cannabis, to tackle the vaping “epidemic”, which has led to at least 530 people taking ill and 8 succumbing to Lung Injury related to the use of...

5 Companies Leveraging CRISPR to Herald the End of Genetic Diseases

CRISPR, which is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary genome editing approach that helps change an individual’s DNA, by altering it at a specific location. The Crisper-Cas9, short for clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9,...

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