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Cyclerion Therapeutics Praliciguat Fails in Two Crucial Clinical Trials

Cyclerion Therapeutics (NASDAQ: CYCN), a clinical-stage Company, announced the failure of its drug candidate praliciguat in meeting the primary endpoints in two separate clinical studies, in diabetic nephropathy (DN) and heart failure with preserved ejection fraction (HFpEF). Praliciguat is a soluble guanylate cyclase (sGC) stimulator...

Emerging Therapeutics in Preeclampsia Management

Preeclampsia is a pregnancy related complication that affects over 5% to 8% of pregnancies or about 3,00,000 women in the US alone. An estimated 10,500 babies in the U.S, succumb to preeclampsia while others suffer from extensive damage owing to premature delivery. It is one of...

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