Cyclerion Therapeutics (NASDAQ: CYCN), a clinical-stage Company, announced the failure of its drug candidate praliciguat in meeting the primary endpoints in two separate clinical studies, in diabetic nephropathy (DN) and heart failure with preserved ejection fraction (HFpEF). Praliciguat is a soluble guanylate cyclase (sGC) stimulator...
Nonalcoholic Steatohepatitis (NASH) is a form of Non-Alcoholic Fatty Liver Disease (NAFLD) and is characterized by the buildup of FAT in the liver. This condition is marked by hepatitis, inflammation, cell damage and fat deposits in the liver. These fat deposits can cause fibrosis of...
The Cannabis plant has an estimated 113 different compounds, out of which THC and CBD are the two main constituents. These affect the receptors in the brain to alter an individual’s physical and mental state. THC is mainly responsible for the psychoactive effects or the...
Focal segmental glomerulosclerosis (FSGS) is a disease caused by the degeneration of glomeruli, the filtering system of the kidney’s and is caused by factors such as diabetes, lupus, sickle cell disease or use of anabolic steroids. It is characterized by a large amount of proteinuria,...
Preeclampsia is a pregnancy related complication that affects over 5% to 8% of pregnancies or about 3,00,000 women in the US alone. An estimated 10,500 babies in the U.S, succumb to preeclampsia while others suffer from extensive damage owing to premature delivery. It is one of...
Stem Cell Therapy is emerging as the future of therapeutics for numerous diseases and disorders which have hitherto been unaddressed. The growing awareness of the regenerative powers of stem cells, along with rising research and development expenditure on stem cell technology will drive the growth...
